VENTILATION EFFICIENCY IMPROVEMENT IN PHARMACEUTICAL CLEANROOMS FOR ENERGY DEMAND REDUCTION

Authors:

P.C.A. Molenaar

Keywords:

Energy savings, Cleanroom finetuning, Overdesigning, Demand controlled filtration, Contaminant removal efficiency

Abstract:

Cleanrooms are large energy consuming facilities due to their high air change rates. This research elaborates on three ventilation energy efficient measures for pharmaceutical cleanrooms: Finetuning, Demand Controlled Filtration (DCF) and an optimal airflow pattern. To study the possibilities for finetuning and DCF, two case studies and multiple simulations were performed. Results show that DCF could lead to substantial energy savings of up to 93.6% in the specific case study facilities. Besides this, DCF based on occupancy could be implemented with a negligible effect on the environmental cleanliness. To study how an ideal airflow pattern in the cleanroom can be reached, resulting in a high contaminant removal efficiency, experiments were performed in a demonstration cleanroom. The best results for ACR in the range of 16h-1 - 38h-1, were obtained when air was supplied without a diffuser above the product area and when the work position was located closely to the air extract grilles.

Article:

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